March 4, 2020

Andrew McDonald
Chief Executive Officer
LifeSci Acquisition Corp.
250 W 55th Street, #3401
New York, NY 10019

       Re: LifeSci Acquisition Corp.
           Amendment No. 2 to Registration Statement on Form S-1
           Filed March 3, 2020
           File No. 333-236466

Dear Mr. McDonald:

       We have reviewed your amended registration statement and have the
following
comment. In our comment, we may ask you to provide us with information so we
may better
understand your disclosure.

       Please respond to this letter by amending your registration statement
and providing the
requested information. If you do not believe our comment applies to your facts
and
circumstances or do not believe an amendment is appropriate, please tell us why
in your
response.

       After reviewing any amendment to your registration statement and the
information you
provide in response to this comment, we may have additional comments.

Form S-1/A

Exhibits

1.     Please reconcile the exclusive forum provision in exhibit 3.2 with your
disclosure on page
       81 or advise.
 Andrew McDonald
FirstName LastNameAndrew McDonald
LifeSci Acquisition Corp.
Comapany NameLifeSci Acquisition Corp.
March 4, 2020
Page 2
March 4, 2020 Page 2
FirstName LastName
       You may contact Jeffrey Lewis at 202-551-6216 or Kristina Marrone at
202-551-3429 if
you have questions regarding comments on the financial statements and related
matters. Please
contact Ronald (Ron) Alper at 202-551-3329 or Brigitte Lippmann at 202-551-3713
with any
other questions.



                                                          Sincerely,

                                                          Division of
Corporation Finance
                                                          Office of Real Estate
& Construction
cc:      Giovanni Caruso